OX40/OX40L in RA

Hypoxia in RA

Introduction Maintaining oxygen homeostasis is of vital importance for the survival and development of mammalian cells. Hypoxia (below-normal levels of oxygen in air, blood and tissue) can potentially lead to cellular dysfunction and ultimately cell death and is a feature of many pathological conditions. Understanding how reduced oxygen levels may contribute to or even promote disease is a sign...

Circadian rhythms in RA.

From patients with arthralgia, pre-RA and recently diagnosed RA: what is the current status of understanding RA pathogenesis?

It is believed that therapy for rheumatoid arthritis (RA) is the most effective and beneficial within a short time frame around RA diagnosis. This insight has caused a shift from research in patients with established RA to patients at risk of developing RA and recently diagnosed patients. It is important for improvement of RA therapy to understand when and what changes occur in patients develop...

RA-915+ Mercury Analyzer

absorption spectrometer with Zeeman background correction, which eliminates the effect of interfering impurities. It is the only high sensitivity and selectivity instrument that does not require gold amalgam pre-concentration and subsequent regeneration steps. This enables the user to conduct real time monitoring and detection of a mercury vapor. Being combined with an RP-91 Cold Vapor accessor...

Mortality in Rheumatoid Arthritis (RA): factors associated with recording RA on death certificates

BACKGROUND Death certificates can be used to assess disease prevalence and incidence; however, rheumatoid arthritis (RA) often remains unreported in death certificates. We sought to determine to what extent RA is underreported and what demographic and clinical characteristics could predict mention of RA in the death certificate. METHODS We recruited 1328 patients with RA from private, public ...